As educators, we are continuously challenged to rethink the way we teach. This is particularly true in the 21st Century in a time of renewed focus on student learning in order to make students in the United States more competitive on a global scale. Many of the US States have adopted the Common Core Standards (http://www.corestandards.org). Another organization, the Partnership for 21st Century Skills (http://p21.org) has developed a framework for K-12 institutions in order to better prepare the students to successfully face rigorous higher education coursework, career challenges and a globally competitive workforce. These 21st Century Skills have been adopted as part of the Common Core State Standards (CCSS) in many states. An alignment with the CCSS is therefore critical to help the students who have been taught with these new standards succeed in higher education.